Intertrigo

Intertrigo may be defined as an inflammation of the body folds. It is a natural skin condition affecting adversing cutaneous or mucocutaneous surfaces. Intertrigo is common in hot humid environments. The condition is a common complication of diabetes. It attacks mostly infants as a component of diaper dermatitis.

Intertrigo refers to the inflammation of skinfolds happens by skin-on-skin friction. Heat and maceration are central point of the process. Erosions will become inflamed when touched to opposing skin. Sweat, feces, urine, and vaginal discharge may enhance intertrigo in both adults and infants Intertrigo is common in those people who are overweight. Intertrigo matures from mechanical factors and secondary infection. Heat and maceration are connections to the process.

Intertrigo is the word used to define a rash in body folds. Affected skin is blushed and uncomfortable. Intertrigo is dependent on the skin part involved and the timings of inflammation. Erythema and weeping can leads to maceration and crusting. Intertrigo is an inflammation of your skin. Rash extends just beyond the dimensions of the opposing skin folds. Satellite blisters are small areas of the same rash that are somewhat close to the main rash, are feture of intertrigo and other Candida skin infections.

Causes of Intertrigo

Common causes of Intertrigo

  • Initiating factors (friction, perspiration, maceration, or irritation from stool).,
  • Autoeczematization.
  • Infection.
  • Candida albicans.
  • Erythrasma.
  • Tinea pedis (athletes foot).
  • Bullous pemphigoid.

Symptoms of Intertrigo

Common Symptoms of Intertrigo

  • Red and moist skin
  • Blisters or scales
  • Cheesy and yeasty.
  • Sweating.
  • Thrush (candidiasis).

Treatment of Intertrigo

Common Treatment of Intertrigo

  • Sweating may be reduced with a gentle antiperspirant .
  • Bacteria may be cured with topical antibiotics ( Petrolatum, zinc oxide, and aluminum acetate ) like fusidic acid cream, mupirocin ointment, or oral antibiotics such as flucloxacillin and erythromycin.
  • Yeasts and fungi can be treated with topical antifungals such as clotrimazole and terbinafine cream or oral agents such as itraconazole or terbinafine
  • Zinc oxide, cod liver oil, and talc and Dimethicone treated Intertrigo.
  • Inflammatory skin diseases are often treated with low potency topical steroid creams such as hydrocortisone.
  • Avoid the flexures as they may cause skin thinning resulting in stretch marks ( striae ) and even ulcers. Calcineurin inhibitors such as tacrolimus ointment or pimecrolimus cream may also prove effective.

0 Comments : 08.18.07

Impetigo

Impetigo is skin infection. It produces blisters sores on the face and hands. It is caused by bacterial infection and distinguished by crusting skin lesions. Impetigo normally visible on the face and especially around a child’s nose and mouth. Other skin disorders may follow it. The skin usually has many types of bacteria on it, but undamaged skin is an effective barrier which keeps bacteria from entering and growing within the body. When there is a cut in the skin, bacteria can reside in the body and grow there, causing inflammation and infection. Cuts in the skin may occur with insect bites, animal bites, or human bites, or other injury or other accidents to the skin. Impetigo may happen on skin where there is no visible break.

The two important types of bacteria that causes impetigo are streptococcal and staphylococcal organisms. It mainly occurs due to bacteria that enters the skin through breaks or insect bites, it can also develop in skin that’s perfectly healthy. Impetigo may follow a current upper respiratory invasion such as a cold or other viral infection. After infection, new blisters may be seen on the patient with no visible break in the skin. However, during some close examination, these blisters will demonstrate some underlying physical damage.

Impetigo is an infection caused by group. A beta-hemolytic streptococci (GABHS) or S aureus. Remnants of ruptured bullae are seen at the time of presentation. Break-up of the epidermis is due to an exotoxin produced by staphylococci, which is the pathologic organism present in cases of bullous impetigo. In lesions of this type, isolation of methicillin-resistant S aureus has been as high as 20%. The organisms are supposed to enter through ruptured skin and are transmitted through direct contact.

Causes of Impetigo

Impetigo that is caused by staphylococcus aureus triggers larger fluid-containing blisters that appear clear, then cloudy. These blisters are more likely to stay intact longer on the skin without bursting. Common causes of Impetigo

  • Streptococcus( GABS).
  • Staphylococcus pyogenes.

Symptoms of Impetigo

Impetigo shows up as a rash that may occur anywhere on the body and commonly affects the face and other exposed areas of the body. Common Symptoms of Impetigo

  • Skin lesion
  • Itching blister:
  • Rash.
  • Lymphadenopathy.
  • Trauma.

Treatment of Impetigo

Common Treatment of Impetigo

  • Avoid close contact with others.
  • Use separate towels and flannels.
  • Cut an infected child’s nails short to prevent scratching.
  • Gently wash the affected areas with mild soap and running water and then cover lightly with gauze.
  • Change and launder clothes and linen daily.

0 Comments : 08.18.07

Hidradenitis Suppurativa

Hidradenitis Suppurativa (HS) is harmful inflammatory skin condition. It is also known as ‘acne inversa’. Hidradenitis Suppurativa differ greatly, it can be as slight as black heads. Hidradenitis suppurativa tends to start after puberty, remains for years and worsen over time. It effects reverse parts of the body, top of inner thighs, bottom, genitals, armpits, under the breasts in women and less commonly the stomach, hair line and behind the ears.

Hidradenitis Suppurativa is a chronic acneiform infection of the related apocrine glands which also may involve adjoining subcutaneous tissue and fascia. The hallmark of the ailment is sinus tracts (which can become draining fistulas) in the apocrine gland body parts. It generally happens on apocrine sweat gland-bearing skin such as in the groin, the underarms and under the breasts. It is more common in women and African Americans. It may carry on in families, but it is not infetious. Poor cleaning does not cause this disease. It usually begins after you become a teenager and before age 40.

Hidradenitis suppurativa is a rarely found acheful skin disease which can be rendering when it progresses to overwhelming systemic infection in an immunocompromised patient.

Premary symptoms is small pitted areas of skin containing blackheads, often appearing in pairs or a “double-barrel” pattern. Secondry symptoms is red, tender bumps (lesions) that fill with pus. The bumps normally enlarge, break open and drain pus. The drainage may have an unpleasant odor. Itching, burning and heavy sweating may comes with the bumps. Wide disease can prevent patients from doing normal work functions and from engaging in normal social activities. In some patients, specially those having severe disease, the situation creates significant psychological problems, particularly regarding sexual relationships.

Causes of Hidradenitis Suppurativa

Common causes of Hidradenitis Suppurativa

  • Crohn disease.
  • Irritable bowel syndrome.
  • Down syndrome.
  • Certain forms of arthritis.
  • Graves disease or Hashimoto thyroiditis.
  • Sjögren syndrome.
  • Herpes simplex.
  • Clogging of the apocrine glands.
  • Stress.
  • Cigarette smoking.
  • Endocrine factors (obesity, hirsutism and acne).

Symptoms of Hidradenitis Suppurativa

Common Symptoms of Hidradenitis Suppurativa

  • Pitted areas of skin.
  • Lesions.
  • Pain.
  • Itching.
  • Burning.
  • Excessive sweating.

Treatment of Hidradenitis Suppurativa

Common Treatment of Hidradenitis Suppurativa

  • Oral retinoid medications to stop oil gland functions and to prevent the plugging of the hair follicle.
  • Nonsteroidal anti-inflammatory drugs to reduce pain and swelling.
  • Corticosteroids or immunosuppressant drugs
  • Antibiotics, ( tetracyclines) long term as a preventive measure, and short term (typically Ciprofloxicillin) for secondary infections.

0 Comments : 08.18.07

Dandruff

Dandruff is due to the excessive shedding of dead skin cells from the scalp. Dandruff can happen at any age but is most common in people between 12-80. Normal cases don’t need nothing more than daily shampooing with a gentle cleanser. Subborn flakes usually respond to medicated shampoos. A yeast-like fungus can cause dandruff, a discovery that may result to better treatment.

Dandruff is an itchy, disturbing and persistent skin disorder of the scalp. Some people, either persistent or because of certain conditions, experience an unusually large amount of flaking, which is also accompanied by redness and irritation. During past ten years dandruff issue in the United States have become more serious. As it is normal that small amount of flaking in fact quite common. Most cases of dandruff are cured with medicated shampoos or common household remedies.

Dandruff is a falling of the skin on the scalp resulting to white flakes on the head, neck, and shoulders. It is a natural condition in which the shedding of dead skin cells happens at an unusually fast rate. As of the oily skin usually related with this condition, these cells deposites together and shed off as dandruff. The scalp skin have many layers.

Dandruff and dark color shirt can relate together, as it looks really akward when someone brushes off the white flakes off your apparel. At the beginning level, dandruff might not seem like a big problem but at later stages it can become troublesome, when skin gets affected. Seborrheic dermatitis is a common skin disorder that can be easily cured.

Dandruff resembles scaling on the scalp without redness. Seborrhea is oiliness of the skin, mainly of the scalp and face not having redness or scaling. Seborrheic dermatitis has both redness and scaling and those patients having seborrhea may later get this.

Causes of Dandruff

Common Causes of Dandruff :

  • Constipation.
  • Exposure to cold.
  • Emotional tension.
  • Usage of harsh shampoos.
  • Stress, anxiety and tension.
  • Cold weather and dry indoor heating.
  • Heredity predisposition.
  • Allergic hypersensitive.
  • Poor health or hygiene.
  • Excessive use of hair sprays and gels.

Symptoms of Dandruff

Some common Symptoms of Dandruff :

  • Itching.
  • Scalp may turn red resulting from scratching.
  • Flakes of skin that range from small and white to large, greasy, and yellow.

Treatment of Dandruff

There are many ways of treating dandruff. The best instrument for dandruf is to wash hair regularly with an appropriate shampoo. Some doctors also recommend the use of anti-fungal agents for the treatment of dandruf, but this remedy is quite controversial. Dandruff, is best cured with a specific anti-dandruf shampoo. To lessen flaking, gently shampoo hair using the pads of finger and try not to starch. Some are -

  • You can also take a spoon full of lemon juice . Mix it with two spoon full of vinegar and massage the mixture on the scalp. Wash your hair with an egg shampoo.
  • Before going to bed oil hair well. Next morning mix 1 tspn  of limejuice with ½ tspn salt. Rub the mixture on the scalp with the peel of a lime turned inside out. Leave for 1 hour before shampooing.
  • Use of antiseptic lotion.
  • Scalp treatment (ozone treatment).
  • Avoid using shampoos with harsh chemicals if you have a bruised scalp. Applying shampoos containing such chemicals on broken skin may cause irritation.
  • In a squirt of lime juice mix one egg yolk and few drops of camphor. Apply it to your scalp for about ten minutes.This will help reintroduce missing protein to your scalp. Rinse with warm water.
  • Important is washing your hair regularly. If you find washing your hair gives you curly or dry ends, the little fact to handle that is to take some conditioner and add it to the ends of your hair before washing it normally. After shampooing, condtion it. if you like to use conditioner.  

0 Comments : 08.16.07

Bullous Pemphigoid

Bullous pemphigoid is a skin disorder. Bullous pemphigoid is a chronic condition. The disorder is reasoned by antibodies and inflammation abnormally forming in a certain layer of the skin called the “basement membrane. It is characterized by large blisters. Bullous pemphigoid (BP) is rare case only seven people in a million form it each year in the UK. Most affected people are aged over 60. It is very rare in children. Men and women are equally affected. BP is not infectious hence you can’t ‘catch’ it from an affected person.

Bullous pemphigoid commonly occurs in older adults. The condition is sometimes life- threatening, but the medications for treating bullous pemphigoid can cause complications. Without treatment, bullous pemphigoid may persist, with periods of pardon and flare-ups, for many time. Bullois Pemphigoid is an autoimmune ailment. In this disease, antibodies are made against the membrane between dermis and epidermis layers of the skin. That means the cells in the body that prevent infection or antibodies attack the skin cells, causing blisters.

Skin becomes provoked (erythematous) and very itchy (pruritic). Its first symptom is redness of the skin surrounding a lesion, scar, and/or the navel. In few weeks, thin walled lesion with clear fluid centers (bullae) forms on the undersurfaces of the arms and legs (flexor surfaces), in the armpits (axillae), on abdomen, and/or around the groin. Apart from Pemphigus, Bullous Pemphigoid lesions mormally do not affect the mucous membrane lining the mouth; if they do they heal rapidly. The lesions formed are usually hard and tight, and contain clear or blood-tinged fluid; they do not break easily. If the lesions do rupture, pain may occur but healing is usually rapid. Bullous Pemphigoid generally itches and in its early stage, itching and patches may be the only symptoms. After a few months, the symptoms of Bullous Pemphigoid usually disappear freely, but they may recur for no apparent reason.

Causes of Bullous Pemphigoid

Common causes of Bullous Pemphigoid :

  • Immunogenetic analyses
  • Trauma.
  • Epitope spreading.
  • Chemokines.
  • Complement activation.

Symptoms of Bullous Pemphigoid

Common Symptoms of Bullous Pemphigoid :

  • Itching..
  • Bullae.
  • Rashes.
  • Mouth sores.
  • Bleeding gums.
  • General ill feeling.
  • Lesions.

Treatment of Bullous Pemphigoid

There is no medical cure for it as such. The disorder can only be kept in controlled with some medications so that it may not become more harmful. The only perfect cure for bullous pemphigoid is time, and as time will pass it will automatically cure on its own. Common Treatment of Bullous Pemphigoid :

  • Immunosuppressive drugs as azathioprine and methotrexate, have been used in combination with corticosteroid drugs to mmedicate Bullous Pemphigoid.
  • Topical Steroids are very effective, usually clobetasol propionate for the fast recovery.
  • Some antibacterial ointment can also be used to prevent skin infection.
  • The skin infection can be controlled by using drugs, like Dapsone, Prednisone and Imuran.
  • The topical cortisone creams can resolve bullous pemphigoid, but sometimes requires high doses of cortisone taken internally.
  • Nicotinamide may also be used in the chronic condition.
  • High dose intravenous immunoglobulin is useful for the reduction of blisters from the skin.
  • Bullous pemphigoid can also require immune suppression drugs, such as azathoprine.

0 Comments : 08.16.07

Blue Nevi

Blue nevus was first desfined as a derived form of melanoma. It is a dark blue - black nevus covered by smooth skin and with minimal or without melanin pigmentation. Amelanotic cellular blue nevus is a cellular blue nevus. Blue nevi can become cancerous when triggered by over exposure to UV rays. Same as other colored moles, these moles should be kept away from being exposed to sunrays. The sun may damage the skin and would turn into melanoma. Blue nevi are solitary papules 2 mm to 1 cm in diameter or, less mainly, plaques, with a bluish color.

Blue nevi are somewhat similar to the Mongolian patch, seen over the sacrum of Asian or African-American children. Blue rubber bleb nevus syndrome (BRBNS) is a ocassional ailment characterized by hemangiomas of the skin and gastrointestinal (GI) tract.

Dysplastic nevi are most common on the trunk. Patients may have one or dozens of dysplastic nevi at the same time. They sometimes occur on sun-protected areas such as buttocks, breasts, and scalp. They usually tend to be larger than common nevi, often greater than 5 mm in diameter.

Blue nevi are most regularly noticed in Asian populations, where the prevalence is estimated to be 3-5% in adults. They are found in 1-2% of white adults and are rarely found in blacks. Blue nevi are uncommon during birth or in the first few years of life, with an estimated usualness of less than 1 case per 1000 population. Both common and cellular blue nevi are not related with chromosomal aberrations, and they show fewer B-RAF mutations compared with congenital and acquired nevi.

Causes of Blue Nevi

Common causes of Blue Nevi :

  • Cold weather.
  • Melanoma.
  • Moles.
  • Aging.
  • Bulging veins.
  • UV radiation trigger.
  • Raynaud’s phenomenon.
  • Weakened Immune System.
  • Sunburns.
  • Xeroderma Pigmentosum.

Symptoms of Blue Nevi

Common Symptoms of Blue Nevi :

  • Itches.
  • Burning sensation.
  • Surrounded by redness.
  • Pain.
  • Lesion.
  • It is dry, rough to the touch and sensitive.
  • Notched or fading borders.

Treatment of Blue Nevi

Common Treatment of Blue Nevi :

  • Pulsed Q-switched laser surgery is a very effective therapy for nevi of Ota and Ito, and it works via selective photothermal and photomechanical destruction of dermal melanocytes and melanophages.
  • Cryotherapy is also very effective in the eradication of damaged part of the skin.
  • Dermabrasion can be used as alone or combined with other modalities, such as carbon dioxide snow, autologous epithelial grafting.
  • Dysplastic moles can also be removed by microscopic evaluation .
  • Use a good sunscreen lotion of minimum SPF-15 and wear a broad-brimmed hat when outdoors.
  • Destroying the abnormal cells is normally done by freezing the skin with liquid nitrogen.

0 Comments : 08.16.07

Blackheads

Blackhead medically name is open comedo. Blackhead is a kind of acne. Blackheads is a skin condition which causes spots. Most people affected by acne are aged between 12 and 25. Allthough, men and women of 30 to 40 can also suffer. Blackheads affects people of all skin types. The processes wshich results in acne are exactly the same in people with black or brown skin but the impact is different by the skin pigmentation. It is caused by excess oils that accumulates in the sebaceous gland ’s duct. Blackheads are basically caused by heavy oil and makeup, that may facilitate the multiplication of the bacterium propionibacterium acnes , the predominant anaerobe of the normal skin flora. The substance found in these formings consists of keratin and modified sebum (an oily secretion of the sebaceous gland ), that darkens (resembling dirt) as it oxidizes.

Two Types of Acne - Primery is Blackheads and secondry whiteheads also known is comedones. It can be in large when on the face and shoulders than red bumps filled with pus. Good consistent skin hygiene may improve this. Blackheads is a clutter of the pilosebaceous unit , made up of a hair follicle, sebaceous gland, and a hair. These units everywhere on the body apart from palms, soles, top of the feet, and the lower lip. The number of pilosebaceous units are mainly on face, upper neck, and chest. Sebaceous glands produce a substance named sebum. It is responsible for keeping the skin and hair moisturized. In adolescence, its production increases because of the influence of hormones.

Causes of Blackheads

The cause of blackhead you can easily deal with it. All is to do is stop the formation of congesting toxins miced up with skin oil and sebum that builds up in sebum channels. Applying anything will not help as blackhead is an internal problem. Common causes of Blackheads :

  • Overactivity of the sebaceous glands.
  • Testosterone.
  • Propionibacterium.
  • Cysts.

Treatment of Blackheads

Common Treatment of Blackheads :

  • Keep spot-prone areas clean.
  • Wash the affected area twice a day with an unperfumed cleanser.
  • Avoid aggressive washing with strong soaps.
  • Antibiotic with other acne medication are available (eg Benzamycin which combines an antibiotic with benzoyl peroxide).
  • Oral antibiotics (tablets), such as tetracycline are prescribed for inflammatory acne.
  • Some types of oral contraceptive tablets help women that faces acne. Combining usual pill hormone called ethinylestradiol and cyproterone acetate (eg Dianette) suppresses male hormone activity so is often effect women with acne.

0 Comments : 08.16.07

Benign Keratosis

Another name for Benign keratoses is seborrheic keratoses. Seborrheic Keratoses (SK) is a skin lesion, whch is most common on sun-exposed areas in older prople. Some patients may have dozens of them, mainly on face, neck and trunk. They have no diseased potential. As they are very superficial lesions, they can be seperated by a variety of methods with little or no scarring. Seborrheic keratosis is a fair type of skin tumor. It commonly visible after age 40. They normally appear on the back or chest and are also common on the scalp, face, arms, and legs.

Seborrheic keratoses builds slowly, in groups or singly. Many people form at least one seborrheic keratosis in their lifetime. The tumors appear as wart-like formations in a different colors. They can appear in numbers on the surface of the body. They are painless and benign, but may creates irritation and itchness. They may be cosmetically disfiguring and psychologically distressing as a consequence.

The most common causes of benign keratosis is Sun exposure. They are increasingly normal in the later decades of life. Children rarely have these skin growths. Seborrheic keratoses mainly affect people older than 30. They developed in some woman during pregnancy or after taking estrogen. Commonly, SKs have sharp borders, a tan-brown-black color, a “glued-on” look, and can be crusty, warty, or sometimes smooth. Occasionally, the surface may decay, mainly when they are picked, they may ooze and bleed. Irritated or irregularly shaped SKs can be inacurate for skin cancer or melanoma.

Causes of Benign Keratosis

Common causes of Benign Keratosis

  • Sun exposure.

Treatment of Benign Keratosis

Common Treatment of Benign Keratosis

  • Cryosurgery is liquid nitrogen, a very cold liquid gas, which is applied to the growth to “freeze” it. A lesion may form under the growth which dries into a scab-like crust. The keratosis mainly drops off within few weeks.
  • Electrosurgery — the growth is anesthetized (numbed) and an electric current is used to burn the growth.
  • Avoid deliberate tanning.
  • Wear long sleeves, pants, a wide-brimmed hat, and sunglasses that protect against both UVA and UVB rays.
  • Use extra caution near water, snow, and sand.
  • Injection and spray is used to anesthetize (numb) the area before the growth is curetted.

0 Comments : 08.16.07

Athlete’s Foot

Athlete’s foot is a skin infection. The situation easily spreads in public places such as communal showers and swimming pools. It is a caused by a fungus and usually occurring between the toes. The fungus can be spread from person to person by touch with these sources. Without correct growing conditions (a warm, moist environment), the fungus cannot affect the skin. Up to 70% of the population will have athletes foot at some time throughout their lives. Athlete foot is also known as tinea pedis. Tinea is a type of fungus, and “pedis” is the Latin word for “foot.” The fungus usually attacks the feet as shoes hatches a warm, dark, and humid environment that enhances fungus growth. When the skin is harmed by the fungus, bacteria can also invade it. These bacteria can cause a bad smell.

Athlete’s foot can expand to the soles of the feet and toenails. It may affets other parts of the body, mainly the groin and underarms, from where who scratch the infection and then contact themselves at other place. The organisms causing athlete’s foot may insists for long time. Athlete’s foot should never be neglected–it can be easily treated, but it also can be very resistant to treatment. Accordingly, the infection can extend by contaminated bed sheets or clothing to other parts of the body.

Causes of Athlete’s Foot

Common causes of Athletes Foot :

  • Dermatophytes.
  • Ringworm fungus.

Symptoms of Athlete’s Foot

Common Symptoms of Athletes Foot :

  • Dry skin.
  • Itching.
  • Scaling.
  • Inflammation.
  • Blisters.
  • Chronic.
  • Leg swelling.
  • Cracking.
  • Pain.
  • Bleeding.

Treatment of Athlete’s Foot

Common Treatment of Athletes Foot :

  • Medicated powders (such as with miconazole ,tolnaftate and clotrimazole), can keep feet dry.
  • Wear socks that keep feet dry, and change them frequently if you sweat heavily.
  • Avoid walking barefoot; use shower shoes.
  • Spray your shoes with a disinfectant and set them in out in the sun to kill germs.
  • Keep home bathroom surfaces clean - especially showers and tubs.
  • Wash feet every day.
  • Change socks daily, and try to change shoes on different days, to allow the shoes to fully dry out.

Prevention Tips

  • Always dry the feet, paying particular attention to the toe webs.
  • After drying, apply anti fungal lotion and continue this with an anti fungal foot powder. Zeasorb AF is effective as it have no cornstarch, a substance which encourages fungal growth.
  • Change socks and underwear every day, especially in warm weather.
  • Avoid walking barefoot in public areas. Instead, wear “flip-flops,” sandals or water shoes.
  • Don’t wear thick clothing for long periods in warm weather. It will make perspire more.
  • Throw away worn-out exercise shoes.
  • Wear waterproof sandals in public showers and pools.

0 Comments : 08.16.07

Aphthous Ulcers

Aphthous ulcers are a common and aching problem. Aphthous ulcers can be categorised into three variant types: minor, major and herpetiform. Minor aphthae are often spotted on labial or buccal mucosa, the soft palate and the floor of the mouth. Major aphthae are larger and comprises deeper ulceration. Aphtha means ulcer which has been used for many years to define parts of ulceration on mucous membranes. Major aphthae can also be more likely to hurt with healing. Herpetiform aphthae naturally are more in number and have vesicles in terms of morphology. Patients with favourable aphthous ulcers should have no other cramps such as fever, adenopathy, gastrointestinal symptoms or other skin or mucous-membrane symptoms.

Aphthous stomatitis is a condition which is characterized by recurrent discrete areas of ulcerationIt is starts in childhood or adolescence as recurrent small, round, or ovoid ulcers with circumscribed margins, erythematous haloes, and yellow or gray floors. Few lesions have also have mast-cell activation and degranulation. The primary disorder appears to be the result of activation of the cell-mediated immune system. Early lesions show a cluster of macrophages and lymphocytes (predominantly cytotoxic and natural-killer T cells) at the pre-ulcerative base, proceeds by deelopment of an ulcer having a neutrophilic base and an erythematous lymphocytic ring.

Causes of Aphthous Ulcers

Common causes of Aphthous Ulcers

  • Hematinic ( iron, folic acid and vitamin B-12) deficiencies.
  • Hypersensitivity reactions
  • Trauma.
  • Genetic predisposition(human leukocyte antigen).
  • Aphthouslike ulceration .
  • Psychological illness and sex hormone levels.

Symptoms of Aphthous Ulcers

Common Symptoms of Aphthous Ulcers

  • Fever..
  • Genital or conjunctival lesions..
  • Headache.
  • Cough.
  • Nausea.
  • Vomiting.
  • Abdominal pain.
  • Diarrhea.
  • Sore throat.
  • Swollen or painful lymphadenopathy.
  • Rash.

Treatment of Aphthous Ulcers

Common Treatment of Aphthous Ulcers

  • Early data shows treatment at onset may reduce symptoms or eradicate ulcer development. Initial studies of the use of 5% amlexanox paste at the onset of burning or pricking mucosal sensation 1-2 days before the ulcer appears can drains the pain.
  • Thalidomide has been effective in unresponsive aphthous stomatitis and in Behçet syndrome.
  • Local injectable anesthetics are necessary in patients with more severe pain. Injectable anesthetics are effective, but relief is brief.
  • High-potency corticosteroid gels, creams, or ointments (with or without adhesive bases) have proven effective in raising healing and shortening the clinical course of RAU.

0 Comments : 08.16.07

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